Collagen Complete: The Science of Skin Rejuvenation

Feb 16, 2025

You know that feeling? When you look in the mirror in the morning, you see tired, dull skin, and you wonder where your natural radiance has gone. The good news: With Collagen Complete from holistic/berlin, we've developed a scientifically proven solution that makes your skin glow from within.

Why collagen is so important

Science has clearly demonstrated that starting at age 25, our body loses approximately 1.5% of its collagen production annually. By age 45, we have already lost 30% of our skin's collagen (Varani et al., 2006, American Journal of Pathology). The consequences of this natural aging process are not only visible but also noticeable: Wrinkles appear, the skin loses elasticity, and our joints also react with reduced mobility.

The innovative formula of Collagen Complete

At the heart of our formula is 2100 mg of high-quality marine collagen types 1 & 3. These collagen peptides are extracted from sustainably sourced marine fish and are characterized by their particularly small molecular size. Scientific studies have shown that marine collagen peptides stimulate the body's own collagen production and can plump wrinkles from within (Proksch et al., 2014, Skin Pharmacology and Physiology).

The power of synergy

What makes Collagen Complete unique is the scientifically based combination of valuable ingredients:

Natural vitamin C from acerola cherries

  • Activates collagen synthesis as an essential co-factor by stimulating the key enzymes prolyl and lysyl hydroxylase (Pullar et al., 2017, Nutrients)
  • Contains up to 30 times more natural vitamin C than citrus fruits (Vendramini et al., 2012)
  • Protects against free radicals and UV-induced skin damage through antioxidant action
  • Supports your skin barrier by promoting ceramide and lipid synthesis in the epidermis
  • Studies show: Vitamin C can increase collagen synthesis in skin fibroblasts by up to 8 times (Nusgens et al., 2001)

Vital trace elements

  • Zinc, copper and manganese act as essential cofactors in collagen formation
  • Copper is essential for the cross-linking of collagen fibers and gives the connective tissue stability
  • Manganese activates the enzymes prolidase and lysyl oxidase, which stimulate collagen and elastin production
  • Scientific studies confirm the importance of these trace elements for a firm, even skin tone (Gupta et al., 2014, Journal of Trace Elements in Medicine and Biology)

Natural sulfur compounds

  • MSM and bamboo extract provide bioactive sulfur
  • Stabilize the collagen structure by forming disulfide bridges
  • Strengthen your hair and nails by supporting keratin cross-linking
  • Clinical studies demonstrate the positive effects of MSM on skin quality and collagen cross-linking (Murad et al., 2015, Natural Medicine Journal)

Essential amino acids

  • L-proline and L-lysine are, along with glycine, the main amino acids in collagen
  • Are incorporated directly into the collagen triple helix
  • Optimize collagen production in fibroblasts
  • Proven to improve collagen density in your skin

Plant bioflavonoids

  • Quercetin and rutin are highly potent secondary plant substances
  • Antioxidants protect against UV-induced skin damage and environmental influences
  • Improve microcirculation in your skin
  • Synergistically support the effect of vitamin C (Choi et al., 2019, Antioxidants)

Scientifically proven effect

The clinical results are impressive: Studies show a significant improvement in skin elasticity and wrinkle depth after just 4 weeks. After 12 weeks of regular use, the skin's collagen density increases by up to 60% (Proksch et al., 2014). Not only your skin, but also your joints, tendons, and bones benefit from the holistic effect (Bello & Oesser, 2006, Current Medical Research and Opinion).

Holistic beauty from within

Collagen Complete is more than just a regular collagen supplement—it's your scientifically sound investment in timeless beauty and vitality. The carefully balanced ingredients work synergistically to support your natural beauty from within.

The effect is based on three pillars:

  1. Targeted supply of highly available collagen peptides
  2. Activation of the body's own collagen production
  3. Protection of the existing collagen structure from degradation

Discover the holistic/berlin difference and experience for yourself how your skin comes alive with new strength and radiance.



Scientific sources:

  • Varani et al. (2006), American Journal of Pathology
  • Proksch et al. (2014), Skin Pharmacology and Physiology
  • Pullar et al. (2017), Nutrients
  • Vendramini et al. (2012), Food Research International
  • Nusgens et al. (2001), Journal of Investigative Dermatology
  • Gupta et al. (2014), Journal of Trace Elements in Medicine and Biology
  • Murad et al. (2015), Natural Medicine Journal
  • Choi et al. (2019), Antioxidants
  • Bello & Oesser (2006), Current Medical Research and Opinion

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